SCHEMBL8632003

SCHEMBL8632003

C=CC(=O)NCC(O)CNC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPK1 P28482 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
TGM2 P21980 3/20 0.38
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147912 0.89 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL8423501 0.87 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL16060 0.87 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9972366 0.87 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL16255465 0.87 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL1548741 0.85
SCHEMBL9889643 0.85 ALDH1A1 (0.56) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28342820 0.85 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
Hydrochloric Acid SCHEMBL28391003 0.85 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL6021854 0.83 ZDHHC20 (0.47) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12122859-B2 Hydrophilic polymeric particles and methods for making and using same LIFE TECHNOLOGIES AS (NO) 2024-10-22 US claimed
EP-3702383-B1 POLYMER SUBSTRATES FORMED FROM CARBOXY FUNCTIONAL ACRYLAMIDE LIFE TECHNOLOGIES CORP (US) 2023-12-27 EP claimed
US-20230167210-A1 Hydrophilic Polymeric Particles and Methods for Making and Using Same Life Technologies Corporation 2023-06-01 US claimed
US-11572427-B2 Hydrophilic polymeric particles and methods for making and using same Life Technologies Corporation (US) 2023-02-07 US claimed
EP-2812360-B1 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING SAME LIFE TECHNOLOGIES CORP (US) 2022-08-31 EP claimed
US-20210155726-A1 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING AND USING SAME LIFE TECHNOLOGIES AS (NO) 2021-05-27 US claimed
CN-108064253-B Polymer matrices formed from carboxy-functional acrylamides 生命技术公司 2020-09-15 CN claimed
EP-3702383-A1 POLYMER SUBSTRATES FORMED FROM CARBOXY FUNCTIONAL ACRYLAMIDE Life Technologies Corporation (US) 2020-09-02 EP claimed
US-20190233558-A1 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING AND USING SAME LIFE TECHNOLOGIES AS (US) 2019-08-01 US claimed
US-10189956-B2 Polymer substrates formed from carboxy functional acrylamide LIFE TECHNOLOGIES AS (NO) 2019-01-29 US claimed
US-9487603-B2 Hydrophilic polymeric particles and methods for making and using same Life Technologies Corporation (US) 2016-11-08 US claimed
US-20160097095-A1 Hydrophilic Polymeric Particles and Methods for Making and Using Same Life Technologies Corporation 2016-04-07 US claimed
US-9243085-B2 Hydrophilic polymeric particles and methods for making and using same Life Technologies Corporation (US) 2016-01-26 US claimed
US-9156925-B2 Hydrophilic polymeric particles and methods for making and using same Life Technologies Corporation (US) 2015-10-13 US claimed
EP-2812360-A2 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING SAME Life Technologies Corporation (US) 2014-12-17 EP claimed
US-20140073715-A1 Hydrophilic Polymeric Particles and Methods for Making and Using Same LIFE TECHNOLOGIES AS (NO) 2014-03-13 US claimed
US-20130210991-A1 Hydrophilic Polymeric Particles and Methods for Making and Using Same Life Technologies Corporation (US) 2013-08-15 US claimed
WO-2013119936-A2 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING SAME Life Technologies Corporation (US) 2013-08-15 WO claimed
US-4511646-A Ethylenically-unsaturated dextrin composition for preparing a durable hydrophilic photopolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-16 US claimed
US-4507382-A Water developable positive acting lithographic printing plate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167210-A1 Hydrophilic Polymeric Particles and Methods for Making and Using Same CD44, CD68, MTDH TSHR 4079/4885ALDH1A1 3456/4885MAPK1 3958/4885
US-20190233558-A1 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING AND USING SAME CD44, CD68, MTDH TSHR 4079/4885ALDH1A1 3456/4885MAPK1 3958/4885
US-20210155726-A1 HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING AND USING SAME CD44, CD68, MTDH TSHR 4079/4885ALDH1A1 3456/4885MAPK1 3958/4885
US-11572427-B2 Hydrophilic polymeric particles and methods for making and using same CD44, CD68, MTDH TSHR 4079/4885ALDH1A1 3456/4885MAPK1 3958/4885
US-12122859-B2 Hydrophilic polymeric particles and methods for making and using same CD44, CD68, MTDH TSHR 4079/4885ALDH1A1 3456/4885MAPK1 3958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.