Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.51 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.51 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500593 | 0.81 | CYP3A4 (0.44) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL7228772 | 0.77 | TSHR (0.41) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL7749473 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL909526 | 0.76 | TSHR (0.44) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL9765088 | 0.74 | TSHR (0.53) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL9386232 | 0.73 | TDP1 (0.46) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL7617600 | 0.73 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL6152635 | 0.73 | TSHR (0.43) | ALDH1A1CYP3A4TSHRTDP1GPR35 | |
| SCHEMBL28419738 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TSHRALOX15HPGD | |
| SCHEMBL6501572 | 0.72 | TSHR (0.48) | ALDH1A1CYP3A4TSHRALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756522-A | INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0780381-A1 | Triazole derivatives and uses thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5369116-A | Polyfluorinated thiazoline derivative and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-11-29 | — | — | US | disclosed |