Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.38 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749473 | 0.85 | ALDH1A1 (0.44) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL7228772 | 0.82 | TSHR (0.41) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL1531096 | 0.80 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL6501572 | 0.80 | TSHR (0.48) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL11449422 | 0.77 | MAPT (0.41) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL13836301 | 0.77 | TDP1 (0.46) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL7481399 | 0.77 | TDP1 (0.46) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL909526 | 0.76 | TSHR (0.44) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL7744893 | 0.73 | TSHR (0.46) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL6152635 | 0.73 | TSHR (0.43) | TDP1ALDH1A1TSHRCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339286-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| WO-1994021597-A1 | ANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |
| EP-0202169-B1 | NEW PYRAZOLE DERIVATIVES, THEIR PRODUCTION AND USES | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1992-11-19 | — | — | EP | disclosed |
| CN-87100152-A | The compound of weeding | — | 1987-08-12 | — | — | CN | disclosed |
| EP-0202169-A1 | New pyrazole derivatives, their production and uses | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, BCHE | TDP1 4282/4885ATM 3640/4885ALDH1A1 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.