Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501699 | 0.85 | LMNA (0.38) | BRS3MAPTLMNAAURKACSNK1E | |
| SCHEMBL8432538 | 0.82 | EDNRA (0.40) | BRS3MAPTLMNAEDNRAKMT2A | |
| SCHEMBL7499419 | 0.81 | EDNRA (0.45) | BRS3EDNRAAURKACSNK1EGSK3A | |
| SCHEMBL7502700 | 0.77 | EDNRA (0.43) | BRS3EDNRAKDM4EALDH1A1HPGD | |
| SCHEMBL8434942 | 0.73 | BRS3 (0.42) | BRS3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8431736 | 0.73 | BRS3 (0.42) | BRS3MAPTLMNAEDNRAAURKA | |
| SCHEMBL8434873 | 0.72 | EDNRA (0.45) | BRS3MAPTEDNRAAURKACSNK1E | |
| SCHEMBL7501396 | 0.72 | EDNRA (0.45) | BRS3LMNAEDNRAKDM4EALDH1A1 | |
| SCHEMBL7496916 | 0.72 | EDNRA (0.54) | BRS3EDNRA | |
| SCHEMBL8435081 | 0.72 | EDNRA (0.44) | BRS3EDNRAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811444-A | IMIDAZOLE DERIVATIVES | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |