Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | STK4 | Q13043 | 1/20 | 0.40 |
| ▸ | STK3 | Q13188 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997920 | 0.84 | LMNA (0.42) | LMNAARHTTHSD17B10ALDH1A1 | |
| SCHEMBL3953577 | 0.72 | AR (0.47) | LMNAARHTTHSD17B10ALDH1A1 | |
| SCHEMBL8667266 | 0.72 | KDM4E (0.51) | LMNAHTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL28431276 | 0.69 | HTT (0.46) | LMNAARHTTHSD17B10ALDH1A1 | |
| SCHEMBL15362290 | 0.68 | HTR7 (0.62) | LMNAARHTTHSD17B10ALDH1A1 | |
| SCHEMBL8664432 | 0.67 | LMNA (0.47) | LMNAARHTTHSD17B10ALDH1A1 | |
| SCHEMBL3996329 | 0.67 | CNR2 (0.42) | LMNAARHTTHSD17B10ALDH1A1 | |
| SCHEMBL11567511 | 0.66 | KDM4E (0.44) | LMNAHTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL891578 | 0.65 | LMNA (0.36) | LMNAHTTHSD17B10ALDH1A1HPGD | |
| SCHEMBL5133066 | 0.65 | LMNA (0.72) | LMNAARHTTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852006-A | N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |