Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754803 | 0.75 | NCF1 (0.44) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3763677 | 0.72 | PDE4A (0.46) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3770950 | 0.71 | KMT2A (0.48) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3763028 | 0.70 | LMNA (0.35) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3760258 | 0.70 | HTT (0.38) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3757772 | 0.69 | HSD17B10 (0.40) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL8664845 | 0.67 | LMNA (0.43) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL6814073 | 0.67 | HTT (0.44) | HTTALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3759709 | 0.67 | NPY5R (0.32) | ALDH1A1HSD17B10TSHRMAPK1NPC1 | |
| SCHEMBL3998045 | 0.67 | ADRB1 (0.43) | ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |