Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958112 | 0.78 | HTR2A (0.55) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL11227371 | 0.78 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL8663600 | 0.78 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL8667753 | 0.77 | CA1 (0.54) | HDAC1HDAC10HDAC6CA1CA2 | |
| SCHEMBL5793241 | 0.74 | KDM4E (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL32665750 | 0.73 | GPR3 (0.46) | KDM4EMEN1KMT2AIMPDH2ALDH1A1 | |
| SCHEMBL29940205 | 0.73 | GPR3 (0.46) | KDM4EMEN1KMT2AIMPDH2ALDH1A1 | |
| SCHEMBL3890065 | 0.73 | GPR3 (0.46) | KDM4EMEN1KMT2AIMPDH2ALDH1A1 | |
| SCHEMBL29824262 | 0.66 | LMNA (0.36) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL31486825 | 0.65 | HTR2A (0.56) | HTR2AHTR2CKDM4EHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830911-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS; ALZHEIMER'SDISEASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |