Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664937 | 0.77 | HDAC3 (0.37) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL25086077 | 0.76 | CA1 (0.48) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL27282251 | 0.74 | CA1 (0.61) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL9059934 | 0.74 | CA1 (0.57) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL8572018 | 0.74 | CA1 (0.57) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL21653604 | 0.74 | CA1 (0.57) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL11755532 | 0.74 | CA1 (0.62) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL3927394 | 0.74 | HTR2A (0.67) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL30223611 | 0.74 | HTR2A (0.67) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL3890065 | 0.74 | GPR3 (0.46) | KDM4EMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830911-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS; ALZHEIMER'SDISEASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |