Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906629 | 0.86 | HSD11B1 (0.34) | THRBCYP2C9 | |
| SCHEMBL6813106 | 0.74 | THRB (0.33) | THRBCYP2C9SLC1A2 | |
| SCHEMBL865316 | 0.69 | CYP19A1 (0.43) | THRBCYP2C9ALDH1A1TSHRMEN1 | |
| SCHEMBL9665581 | 0.68 | GRM4 (0.31) | CYP2C9ALDH1A1GRM4CYP1A2CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL4339903 | 0.67 | CYP19A1 (0.42) | THRBCYP2C9ALDH1A1TSHRMEN1 | |
| SCHEMBL8663610 | 0.67 | THRB (0.48) | THRBCYP2C9TSHRLMNASLC22A2 | |
| SCHEMBL9667781 | 0.65 | — | — | |
| SCHEMBL5880685 | 0.64 | CYP17A1 (0.43) | TSHRMEN1KMT2A | |
| SCHEMBL5179241 | 0.63 | POLB (0.50) | THRBCYP2C9TSHRLMNASLC22A2 | |
| SCHEMBL25509617 | 0.63 | HSD11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750489-B1 | INHIBITION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1998-11-18 | — | — | EP | claimed |