Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386470 | 0.84 | CES1 (0.50) | ALDH1A1NOS1IDO1NOS3NOS2 | |
| SCHEMBL8665089 | 0.79 | KEAP1 (0.64) | GRIN1GRIN2BKEAP1ALDH1A1FFAR1 | |
| SCHEMBL5184956 | 0.75 | KEAP1 (0.58) | GRIN1GRIN2BKEAP1ALDH1A1NOS1 | |
| Hydroxyamine SCHEMBL2782141 | 0.74 | MAOA (0.65) | KEAP1ALDH1A1IDO1FFAR1TDP1 | |
| SCHEMBL5071007 | 0.74 | CES1 (0.60) | ALDH1A1IDO1TDP1L3MBTL1LOXL2 | |
| SCHEMBL27579179 | 0.73 | KEAP1 (0.57) | KEAP1ALDH1A1FFAR1TDP1L3MBTL1 | |
| SCHEMBL7392796 | 0.73 | KEAP1 (0.56) | GRIN1GRIN2BKEAP1ALDH1A1FFAR1 | |
| SCHEMBL10685859 | 0.73 | KEAP1 (0.56) | GRIN1GRIN2BKEAP1ALDH1A1FFAR1 | |
| SCHEMBL5371385 | 0.73 | KEAP1 (0.56) | GRIN1GRIN2BKEAP1ALDH1A1FFAR1 | |
| SCHEMBL12127745 | 0.72 | GRIN1 (0.66) | GRIN1GRIN2BKEAP1ALDH1A1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194724-B | Compound containing diphenylmethane structure and application thereof | 广州同隽医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |