Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 9/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500946 | 0.94 | CCR3 (0.36) | CCR3MCHR1DRD2DRD4SLC6A12 | |
| SCHEMBL8668038 | 0.84 | CCR3 (0.41) | CCR3MCHR1DRD2DRD4SLC6A12 | |
| SCHEMBL8666049 | 0.83 | L3MBTL1 (0.34) | — | |
| SCHEMBL8665883 | 0.83 | NPSR1 (0.37) | CCR3MCHR1DRD2DRD4NPSR1 | |
| SCHEMBL8484436 | 0.81 | L3MBTL1 (0.37) | — | |
| SCHEMBL8666099 | 0.81 | NPSR1 (0.36) | CCR3MCHR1DRD2DRD4NPSR1 | |
| SCHEMBL8483744 | 0.80 | CCR3 (0.44) | CCR3MCHR1SLC6A12TMEM97SIGMAR1 | |
| SCHEMBL8665212 | 0.79 | CCR3 (0.39) | CCR3MCHR1DRD2DRD4SLC6A12 | |
| SCHEMBL8479389 | 0.79 | DPP4 (0.38) | MCHR1NPSR1 | |
| SCHEMBL8485545 | 0.78 | NPSR1 (0.40) | CCR3MCHR1SLC6A12TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |