Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD4 | P21917 | 6/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666099 | 0.98 | NPSR1 (0.36) | NPSR1DRD2DRD4UTS2RCTSL | |
| SCHEMBL8485545 | 0.95 | NPSR1 (0.40) | NPSR1POLBCARM1PRMT6MCHR1 | |
| SCHEMBL8501239 | 0.94 | NPSR1 (0.33) | NPSR1DRD2DRD4UTS2RPOLB | |
| SCHEMBL8484461 | 0.93 | NPSR1 (0.39) | NPSR1POLBCARM1PRMT6MCHR1 | |
| SCHEMBL8501052 | 0.92 | NPSR1 (0.33) | NPSR1DRD2DRD4POLBCHRM1 | |
| SCHEMBL8669690 | 0.91 | UTS2R (0.39) | NPSR1DRD2DRD4UTS2RCTSL | |
| SCHEMBL8664874 | 0.89 | DRD2 (0.33) | DRD2UTS2RMCHR1MEN1KMT2A | |
| SCHEMBL8665520 | 0.89 | CCR3 (0.42) | NPSR1DRD2CCR3 | |
| SCHEMBL8668038 | 0.88 | CCR3 (0.41) | NPSR1DRD2DRD4MCHR1CCR3 | |
| SCHEMBL8665531 | 0.87 | CCR3 (0.41) | NPSR1DRD2CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |