SCHEMBL8665226

SCHEMBL8665226

CS(=O)(=O)c1nc(Oc2cccc(C(F)(F)F)c2)cc(C(F)(F)F)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SDHB P21912 7/20 0.58
KDM4E B2RXH2 7/20 0.53
ALDH1A1 P00352 7/20 0.53
MAPT P10636 3/20 0.49
NPSR1 Q6W5P4 8/20 0.49
LMNA P02545 5/20 0.49
HPGD P15428 5/20 0.49
KMT2A Q03164 4/20 0.49
TP53 P04637 4/20 0.49
HTT P42858 4/20 0.49
STAT3 P40763 4/20 0.49
RAB9A P51151 4/20 0.49
HSD17B10 Q99714 3/20 0.49
MEN1 O00255 2/20 0.49
S1PR4 O95977 2/20 0.49
POLB P06746 2/20 0.49
S1PR1 P21453 2/20 0.49
MAPK1 P28482 2/20 0.49
STAT1 P42224 2/20 0.49
TLR9 Q9NR96 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31287948 0.92 ALDH1A1 (0.57) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8669893 0.88 ALDH1A1 (0.53) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8670000 0.88 LMNA (0.55) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8665887 0.88 ALDH1A1 (0.62) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8666828 0.86 ALDH1A1 (0.52) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8666413 0.86 ALDH1A1 (0.52) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8720496 0.84 ALDH1A1 (0.50) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8665287 0.84 ALDH1A1 (0.50) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8669831 0.82 ALDH1A1 (0.53) SDHBKDM4EALDH1A1MAPTNPSR1
SCHEMBL8668641 0.81 ALDH1A1 (0.47) SDHBKDM4EALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723412-A HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
EP-0694538-A2 2-benzyloxy-4-phenoxypyrimidine derivative, processes for producing the derivative and herbicidal composition containing the derivative KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-31 EP disclosed