SCHEMBL8665287

SCHEMBL8665287

CCOc1cc(Oc2cccc(C(F)(F)F)c2)nc(S(C)(=O)=O)n1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPK1 P28482 2/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
LMNA P02545 1/20 0.46
SDHB P21912 2/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
NTRK1 P04629 1/20 0.41
RAB9A P51151 1/20 0.40
GAA P10253 2/20 0.40
TDP1 Q9NUW8 1/20 0.39
LTA4H P09960 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31287948 0.92 ALDH1A1 (0.57) ALDH1A1KDM4EMAPK1L3MBTL1POLB
SCHEMBL8670000 0.87 LMNA (0.55) ALDH1A1KDM4EMAPK1L3MBTL1POLB
SCHEMBL8668641 0.87 ALDH1A1 (0.47) ALDH1A1KDM4EMAPK1L3MBTL1POLB
SCHEMBL8669893 0.84 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1POLBMAPT
SCHEMBL8665887 0.84 ALDH1A1 (0.62) ALDH1A1KDM4EL3MBTL1POLBMAPT
SCHEMBL8665226 0.84 SDHB (0.58) ALDH1A1KDM4EMAPK1L3MBTL1POLB
SCHEMBL8666413 0.83 ALDH1A1 (0.52) ALDH1A1KDM4EMAPK1L3MBTL1POLB
SCHEMBL8666828 0.83 ALDH1A1 (0.52) ALDH1A1KDM4EL3MBTL1POLBMAPT
SCHEMBL8669831 0.82 ALDH1A1 (0.53) ALDH1A1KDM4EMAPK1L3MBTL1POLB
SCHEMBL8720496 0.81 ALDH1A1 (0.50) ALDH1A1KDM4EMAPK1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723412-A HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
EP-0694538-A2 2-benzyloxy-4-phenoxypyrimidine derivative, processes for producing the derivative and herbicidal composition containing the derivative KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-31 EP disclosed