SCHEMBL866531

SCHEMBL866531

CC(C)OC(=O)N1CCC(Oc2ccc(-c3ccc(CC(N)C(=O)N4CCC[C@H]4C#N)c(F)c3)cn2)CC1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.51
DPP8 Q6V1X1 14/20 0.51
DPP9 Q86TI2 14/20 0.51
FAP Q12884 10/20 0.51
DPP7 Q9UHL4 9/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866532 1.00 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL866530 1.00 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL865754 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL865753 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL10101227 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL865401 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL866034 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL865403 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL865402 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7
SCHEMBL10104974 0.92 DPP4 (0.51) DPP4DPP8DPP9FAPDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077793-A1 Compounds for the Treatment of Metabolic Disorders PROSIDION LIMITED (GB) 2012-03-29 US claimed
US-20120077793-A1 Compounds for the Treatment of Metabolic Disorders PROSIDION LIMITED (GB) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120077793-A1 Compounds for the Treatment of Metabolic Disorders GPR119, GPR132, FFAR2 DPP4 217/4885DPP8 615/4885DPP9 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.