SCHEMBL8665357

SCHEMBL8665357

CCCCC(CC)C/C=C\C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
BACE1 P56817 1/20 0.46
CA2 P00918 4/20 0.46
ALDH1A1 P00352 3/20 0.45
TSHR P16473 3/20 0.44
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2069188 1.00 ACHE (0.46) ACHEBACE1CA2ALDH1A1TSHR
SCHEMBL10582207 0.93 HCAR2 (0.45) ACHEBACE1HCAR2
SCHEMBL10459468 0.93 HCAR2 (0.45) ACHEBACE1HCAR2
Biphenyl SCHEMBL27872150 0.88 ALDH1A1 (0.46) ACHEBACE1CA2ALDH1A1TSHR
SCHEMBL1859961 0.86 PTPN1 (0.41) ALDH1A1
SCHEMBL28113315 0.85 CA2 (0.46) CA2ALDH1A1TSHRMAPK1CYP3A4
SCHEMBL18595177 0.85 HCAR2 (0.47) ACHEBACE1HCAR2
SCHEMBL15572905 0.84 CA2 (0.44) CA2ALDH1A1TSHRMAPK1CYP3A4
SCHEMBL9763272 0.84 CA2 (0.49) ACHEBACE1CA2ALDH1A1TSHR
SCHEMBL4444563 0.84 CA2 (0.44) CA2ALDH1A1TSHRMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0401200-B2 Copolymer and its use BCD ROHSTOFFE FUER BAUCHEMIE H (AT) 1998-12-09 EP disclosed