Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546812 | 0.85 | MEN1 (0.47) | MEN1KMT2ALMNAATMHSD17B10 | |
| SCHEMBL6547367 | 0.79 | MEN1 (0.53) | MEN1KMT2ALMNAATMHSD17B10 | |
| SCHEMBL12506256 | 0.78 | HTR2A (0.56) | LMNAHKDC1TDP1HTR2AHRH1 | |
| SCHEMBL894135 | 0.78 | MEN1 (0.65) | MEN1KMT2ALMNAATMHSD17B10 | |
| SCHEMBL27344332 | 0.76 | LMNA (0.50) | LMNAHSD17B10MAPTHTTALDH1A1 | |
| SCHEMBL29057338 | 0.76 | ALDH1A1 (0.53) | LMNAHSD17B10MAPTHTTCYP3A4 | |
| SCHEMBL24355054 | 0.75 | MEN1 (0.53) | MEN1KMT2AATMHSD17B10MAPT | |
| SCHEMBL6546186 | 0.75 | TP53 (0.54) | MEN1KMT2ALMNAATMHSD17B10 | |
| SCHEMBL54346 | 0.75 | HTR2A (0.59) | LMNAHKDC1TDP1HTR2AHRH1 | |
| Ethane SCHEMBL27455181 | 0.75 | MEN1 (0.62) | MEN1KMT2ALMNAATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5690861-A | Coupling of polymers made by cationic polymerization | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 1997-11-25 | — | — | US | claimed |
| US-5777044-A | Coupling of polymers made by cationic polymerization | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 1998-07-07 | — | — | US | disclosed |
| US-5690861-A | Coupling of polymers made by cationic polymerization | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 1997-11-25 | — | — | US | disclosed |