Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494927 | 0.86 | MAPT (0.55) | MAPTNPC1RAB9ASMN1; SMN2ALPL | |
| SCHEMBL8666424 | 0.84 | RHEB (0.44) | MAP2K4KDRFLT1FLT4RHEB | |
| SCHEMBL8078179 | 0.84 | TSHR (0.44) | KDRRHEBALDH1A1MAPTNPC1 | |
| SCHEMBL2494847 | 0.83 | KMT2A (0.41) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11278246 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL1868574 | 0.75 | MGAM (0.42) | MAP2K4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4300304 | 0.75 | SRD5A2 (0.60) | MAP2K4KDRFLT1FLT4RHEB | |
| SCHEMBL2493563 | 0.75 | TSHR (0.45) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL8663910 | 0.74 | TSHR (0.44) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL2497787 | 0.73 | EGFR (0.52) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |