SCHEMBL8666266

SCHEMBL8666266

CCCCO[Si](CC)(OC)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8665400 0.94 DNM1 (0.31) ADRB2ADRB1ADRB3
SCHEMBL5834512 0.89 ADRB2 (0.35) ADRB2ADRB1ADRB3
SCHEMBL8667495 0.87
SCHEMBL8665136 0.83 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL8668645 0.83 DNM1 (0.33)
SCHEMBL703099 0.80 ADRB2 (0.35) ADRB2ADRB1ADRB3
SCHEMBL704156 0.80 ADRB2 (0.35) ADRB2ADRB1ADRB3
SCHEMBL704954 0.78 ADRB2 (0.33) ADRB2ADRB1ADRB3
SCHEMBL703108 0.78 ADRB2 (0.33) ADRB2ADRB1ADRB3
SCHEMBL8670140 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530814-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1998-12-16 EP disclosed
US-5489634-A EFFICIENT SELECTIVE CATALYTIC POLYMERIZATION OF ALPHA-OLEFINS YIELDS HIGH MOLECULAR WEIGHT SPHERICAL PARTICLES HAVING HIGH BULK DENSITY, CONTROLLED PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION TOSOH CORPORATION (JP) 1996-02-06 US disclosed
EP-0582943-A2 Method for producing a polyolefin TOSOH CORPORATION (JP) 1994-02-16 EP disclosed
EP-0530814-A1 Method for producing a stereospecific polyolefin TOSOH CORPORATION (JP) 1993-03-10 EP disclosed