SCHEMBL8668645

SCHEMBL8668645

CCCCCO[Si](CC)(OCCCCC)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.33
CA1 P00915 6/20 0.31
CA2 P00918 6/20 0.31
CA9 Q16790 6/20 0.31
HTT P42858 2/20 0.31
THRB P10828 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA12 O43570 1/20 0.31
MAPT P10636 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TSHR P16473 1/20 0.30
LPAR3 Q9UBY5 4/20 0.30
LPAR2 Q9HBW0 3/20 0.30
LPAR1 Q92633 2/20 0.30
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5834512 0.93 ADRB2 (0.35) TSHR
SCHEMBL8665400 0.90 DNM1 (0.31) DNM1
SCHEMBL8665136 0.87 ADRB2 (0.31)
SCHEMBL5834472 0.83
SCHEMBL8666266 0.83 ADRB2 (0.36)
SCHEMBL703099 0.79 ADRB2 (0.35) TSHR
SCHEMBL704156 0.79 ADRB2 (0.35) TSHR
SCHEMBL704954 0.77 ADRB2 (0.33) TSHR
SCHEMBL703108 0.77 ADRB2 (0.33) TSHR
SCHEMBL8665460 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530814-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1998-12-16 EP disclosed
US-5489634-A EFFICIENT SELECTIVE CATALYTIC POLYMERIZATION OF ALPHA-OLEFINS YIELDS HIGH MOLECULAR WEIGHT SPHERICAL PARTICLES HAVING HIGH BULK DENSITY, CONTROLLED PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION TOSOH CORPORATION (JP) 1996-02-06 US disclosed
EP-0582943-A2 Method for producing a polyolefin TOSOH CORPORATION (JP) 1994-02-16 EP disclosed
EP-0530814-A1 Method for producing a stereospecific polyolefin TOSOH CORPORATION (JP) 1993-03-10 EP disclosed