Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.34 |
| ▸ | RARA | P10276 | 16/20 | 0.34 |
| ▸ | RARG | P13631 | 16/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562602 | 0.80 | RARB (0.35) | RARBRARARARGBACE1RXRA | |
| SCHEMBL8664217 | 0.78 | RARB (0.42) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661085 | 0.78 | RARB (0.46) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661311 | 0.77 | RARB (0.43) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8665967 | 0.76 | RARB (0.42) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8666342 | 0.76 | RARB (0.54) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8664382 | 0.76 | RARB (0.44) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8667411 | 0.75 | RARB (0.43) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661417 | 0.75 | RARB (0.43) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8772764 | 0.75 | RARB (0.33) | RARBRARARARGBACE1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | disclosed |