Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665781 | 0.92 | MAPT (0.46) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8667672 | 0.88 | MAPT (0.40) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8671972 | 0.85 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8670705 | 0.81 | NPY5R (0.35) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8671324 | 0.80 | MPL (0.47) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8667772 | 0.79 | ADORA1 (0.46) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8666532 | 0.76 | MAPT (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8666187 | 0.74 | MAPT (0.37) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8669604 | 0.72 | PKM (0.38) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8673476 | 0.70 | CCNT1 (0.36) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638581-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5480874-A | THIAZOLE AND IMIDAZOLE DERIVATIVES; ANTIHYPERLIPIDEMICS AND HYPOGLYCEMICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0638581-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-15 | — | — | EP | disclosed |