Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.63 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.57 |
| ▸ | UGCG | Q16739 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27357411 | 1.00 | ASAH1 (0.63) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL14960683 | 0.90 | ASAH1 (0.61) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL6571640 | 0.83 | CERT1 (0.65) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL15996628 | 0.83 | LMNA (0.49) | ASAH1ALDH1A1ACER2NPSR1MEN1 | |
| SCHEMBL31043494 | 0.81 | ASAH1 (0.63) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL31043495 | 0.81 | ASAH1 (0.63) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL4786264 | 0.79 | ASAH1 (0.66) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL7139621 | 0.79 | NAAA (0.55) | ASAH1ALDH1A1ACER2CERT1MAPT | |
| SCHEMBL14842114 | 0.79 | ASAH1 (0.66) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL13963519 | 0.79 | ASAH1 (0.66) | ASAH1ALDH1A1ACER2CERT1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625517-B1 | Taxane having antitumor activity | INDENA SPA (IT) | 1998-12-16 | — | — | EP | claimed |
| WO-1994027984-A1 | TAXANE HAVING ANTITUMOR ACTIVITY | INDENA S.P.A. (IT) | 1994-12-08 | — | — | WO | claimed |
| EP-0625517-A1 | Taxane having antitumor activity | INDENA S.p.A. (IT) | 1994-11-23 | — | — | EP | claimed |
| EP-0625517-B1 | Taxane having antitumor activity | INDENA SPA (IT) | 1998-12-16 | — | — | EP | disclosed |
| US-5407674-A | Plant extracts | INDENA S.P.A. (IT) | 1995-04-18 | — | — | US | disclosed |
| WO-1994027984-A1 | TAXANE HAVING ANTITUMOR ACTIVITY | INDENA S.P.A. (IT) | 1994-12-08 | — | — | WO | disclosed |
| EP-0625517-A1 | Taxane having antitumor activity | INDENA S.p.A. (IT) | 1994-11-23 | — | — | EP | disclosed |