Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940289 | 0.82 | SMN1; SMN2 (0.54) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL3277732 | 0.72 | SMN1; SMN2 (0.63) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL3277617 | 0.70 | NPC1 (0.82) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL7818265 | 0.68 | APP (0.74) | NPC1FLT3CA2RAB9AGFER | |
| SCHEMBL9079005 | 0.68 | NPC1 (1.00) | NPC1SMN1; SMN2MAPTRAB9AMAOB | |
| SCHEMBL3920685 | 0.67 | FLT3 (0.59) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL483027 | 0.66 | CA12 (0.60) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL29441432 | 0.66 | CA12 (0.60) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL16284310 | 0.66 | NPC1 (0.57) | NPC1FLT3CA2SMN1; SMN2MAPT | |
| SCHEMBL7803332 | 0.66 | TYR (0.59) | NPC1FLT3CA2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577245-B1 | Photogenerating azo pigments | XEROX CORP (US) | 1998-12-02 | — | — | EP | claimed |