Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666832 | 0.77 | BRAF (0.33) | KDR | |
| SCHEMBL8666414 | 0.62 | BRAF (0.34) | KDR | |
| SCHEMBL8665228 | 0.62 | BRAF (0.34) | SLC22A12KDR | |
| SCHEMBL8665890 | 0.62 | KDR (0.34) | CYP17A1KDRTEK | |
| SCHEMBL8670005 | 0.62 | SCN9A (0.35) | SCN9ACYP17A1KDR | |
| SCHEMBL8669895 | 0.62 | BRAF (0.33) | SCN9APTGS2KDR | |
| SCHEMBL28104979 | 0.61 | HSD17B10 (0.46) | MAP4K4EGFRFRKMAPK9CSNK1A1 | |
| SCHEMBL21629952 | 0.60 | SYK (0.39) | CSNK1A1KDRTEK | |
| SCHEMBL10847294 | 0.60 | PDE3B (0.40) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL27295925 | 0.60 | CYP2D6 (0.49) | CDK2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723412-A | HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-03 | — | — | US | disclosed |