Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394827 | 0.86 | ALDH1A1 (0.35) | ALDH1A1BACE1NPC1RAB9AMEN1 | |
| SCHEMBL6935491 | 0.79 | DYRK1A (0.44) | ADORA2AADORA1BACE1MAOB | |
| SCHEMBL29508349 | 0.79 | DYRK1A (0.44) | ADORA2AADORA1BACE1MAOB | |
| SCHEMBL8665749 | 0.79 | BACE1 (0.39) | ADORA2AADORA1BACE1NPC1RAB9A | |
| SCHEMBL491016 | 0.76 | BACE1 (0.41) | ADORA2AADORA1BACE1MAOAMAOB | |
| SCHEMBL490744 | 0.73 | NPY5R (0.44) | ADORA2AADORA1ALDH1A1NPC1CYP19A1 | |
| SCHEMBL30987503 | 0.73 | ALDH1A1 (0.34) | ALDH1A1BACE1NPC1RAB9AMEN1 | |
| SCHEMBL155813 | 0.73 | ALDH1A1 (0.34) | ALDH1A1BACE1NPC1RAB9AMEN1 | |
| SCHEMBL2534150 | 0.72 | NPC1 (0.41) | ALDH1A1NPC1RAB9ACDK2MEN1 | |
| SCHEMBL2498529 | 0.72 | PTPN1 (0.37) | ALDH1A1BACE1NPC1RAB9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |