Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667148 | 0.95 | RXFP1 (0.34) | RXFP1MEN1KMT2ARAB9ACCR3 | |
| SCHEMBL8667926 | 0.93 | MEN1 (0.37) | RXFP1MEN1KMT2ARAB9ACCR3 | |
| Hydrochloric Acid SCHEMBL8663917 | 0.92 | MEN1 (0.36) | RXFP1MEN1KMT2ARAB9ACCR3 | |
| SCHEMBL8504394 | 0.91 | MEN1 (0.37) | RXFP1MEN1KMT2ARAB9ACCR3 | |
| SCHEMBL8482589 | 0.88 | RXFP1 (0.34) | RXFP1MEN1KMT2ARAB9ACCR3 | |
| SCHEMBL8482592 | 0.87 | RXFP1 (0.34) | RXFP1MEN1KMT2ARAB9ACCR3 | |
| SCHEMBL8668000 | 0.81 | KMT2A (0.37) | MEN1KMT2AGAA | |
| SCHEMBL8480001 | 0.80 | MAPT (0.38) | RXFP1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL8501146 | 0.80 | POLB (0.35) | MEN1KMT2A | |
| SCHEMBL8479944 | 0.80 | MAPT (0.37) | RXFP1MEN1KMT2ARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |