Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 6/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504394 | 0.89 | MEN1 (0.37) | POLBMEN1KMT2A | |
| SCHEMBL8668000 | 0.88 | KMT2A (0.37) | POLBDRD2DRD4DRD3MEN1 | |
| SCHEMBL8667926 | 0.87 | MEN1 (0.37) | POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8663917 | 0.87 | MEN1 (0.36) | POLBMEN1KMT2A | |
| SCHEMBL8483454 | 0.84 | MEN1 (0.35) | POLBELANEFAAHMEN1KMT2A | |
| SCHEMBL8503676 | 0.81 | POLB (0.35) | POLBDRD2DRD4DRD3 | |
| SCHEMBL8713182 | 0.81 | CKS1B (0.38) | POLBELANEDRD2DRD4DRD3 | |
| SCHEMBL8667146 | 0.80 | RXFP1 (0.34) | MEN1KMT2A | |
| SCHEMBL8664872 | 0.79 | SMPD2 (0.37) | POLBELANE | |
| SCHEMBL8593680 | 0.78 | POLB (0.42) | POLBDRD2DRD4DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |