Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667468 | 1.00 | KMT2A (0.32) | KMT2ASMN1; SMN2FFAR1ALDH1A1MAPT | |
| SCHEMBL8667526 | 0.88 | SLC9A1 (0.33) | SLC9A1SLC9A2THRATHRB | |
| SCHEMBL8667529 | 0.88 | SLC9A1 (0.33) | SLC9A1SLC9A2THRATHRB | |
| SCHEMBL8665023 | 0.86 | SMN1; SMN2 (0.33) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL8665020 | 0.86 | SMN1; SMN2 (0.33) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL8666430 | 0.84 | SLC9A1 (0.32) | KMT2ASMN1; SMN2ALDH1A1SLC9A1SLC9A2 | |
| SCHEMBL7798615 | 0.82 | SLC9A1 (0.53) | SLC9A1SLC9A2 | |
| SCHEMBL7798617 | 0.82 | SLC9A1 (0.53) | SLC9A1SLC9A2 | |
| SCHEMBL8664964 | 0.82 | THRA (0.32) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL8664961 | 0.82 | THRA (0.32) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731351-A | Alkenyl-benzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |