SCHEMBL8667620

SCHEMBL8667620

C=CS(=O)(=O)CC(=C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.41
MAOB P27338 4/20 0.41
AKT1 P31749 1/20 0.41
ALDH1A1 P00352 3/20 0.36
CYP2C19 P33261 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9843426 0.80 MAOA (0.38) MAOAMAOBAKT1ALDH1A1CYP2C19
SCHEMBL9843430 0.80 MAOA (0.38) MAOAMAOBAKT1ALDH1A1CYP2C19
SCHEMBL28526172 0.79 MAOA (0.47) MAOAMAOBALDH1A1NPSR1SMN1; SMN2
SCHEMBL2866425 0.78 MAOA (0.45) MAOAMAOBALDH1A1NPSR1SMN1; SMN2
SCHEMBL15413487 0.76 MAOA (0.44) MAOAMAOBNPSR1SMN1; SMN2CA12
SCHEMBL9488126 0.76 MAOA (0.44) MAOAMAOBALDH1A1NPSR1SMN1; SMN2
SCHEMBL9494682 0.74 HSD11B1 (0.52) ALDH1A1CA12CA2CA9KMT2A
SCHEMBL10701243 0.74 MAOA (0.42) MAOAMAOBALDH1A1NPSR1MAPT
SCHEMBL9488123 0.74 MAOA (0.42) MAOAMAOBSMN1; SMN2CA12CA1
Sulfuric Acid SCHEMBL4875618 0.73 MAOA (0.41) MAOAMAOBAKT1ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP claimed
EP-0595275-B1 Photographic light-sensitive elements EASTMAN KODAK CO (US) 1998-12-09 EP disclosed
EP-0595275-A1 Photographic light-sensitive elements EASTMAN KODAK COMPANY (US) 1994-05-04 EP disclosed
EP-0307855-B1 GELATIN-GRAFTED POLYMER PARTICLES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-07-14 EP disclosed
EP-0530357-A1 ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES. EASTMAN KODAK CO (US) 1993-03-10 EP disclosed
WO-1992016659-A1 ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES EASTMAN KODAK COMPANY (US) 1992-10-01 WO disclosed
US-4948480-A DISSOLVING ACRYLAMIDE COPOLYMER IN WATER, ADDING BUFFER, ADDING CROSSLINKING AGENT FROM SEPARATE PACKAGE EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed
US-4855219-A CROSSLINKING EASTMAN KODAK COMPANY (US) 1989-08-08 US disclosed
EP-0307855-A2 Gelatin-grafted polymer particles EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-03-22 EP disclosed