Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644734 | 0.88 | HSD11B1 (0.59) | HSD11B1RECQLALDH1A1MMP2MMP7 | |
| SCHEMBL9721147 | 0.88 | RECQL (0.69) | HSD11B1RECQLPOLBALDH1A1TP53 | |
| SCHEMBL9644695 | 0.88 | HSD11B1 (0.69) | HSD11B1RECQLPOLBALDH1A1CA12 | |
| SCHEMBL9644764 | 0.88 | HSD11B1 (0.69) | HSD11B1RECQLPOLBALDH1A1TP53 | |
| SCHEMBL9644781 | 0.84 | HSD11B1 (0.48) | HSD11B1RECQLPOLBALDH1A1MAPT | |
| SCHEMBL9721136 | 0.84 | HSD11B1 (0.45) | HSD11B1RECQLPOLBPSIP1CA12 | |
| SCHEMBL9644754 | 0.83 | HSD11B1 (0.54) | HSD11B1POLBALDH1A1TP53HTT | |
| SCHEMBL28526172 | 0.81 | MAOA (0.47) | RECQLPOLBALDH1A1HTTMAPT | |
| SCHEMBL24106342 | 0.79 | MAPT (0.53) | HSD11B1RECQLPOLBALDH1A1HTT | |
| SCHEMBL2866425 | 0.79 | MAOA (0.45) | RECQLPOLBALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645895-B | Isoxazoline derivative with olefin side chain and synthesis method thereof | 浙江工业大学 | 2022-07-26 | — | — | CN | disclosed |
| US-20210221766-A1 | METHOD FOR PRODUCING FLUORINATED COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2021-07-22 | — | — | US | disclosed |
| CN-112645895-A | Isoxazoline derivative with olefin side chain and synthesis method thereof | 浙江工业大学 | 2021-04-13 | — | — | CN | disclosed |
| EP-3166568-A1 | DENTAL MATERIALS HAVING DEBONDING-ON-DEMAND PROPERTIES | Ivoclar Vivadent AG (LI) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005540-A1 | DENTAL MATERIALS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2016-01-14 | — | — | WO | disclosed |
| EP-0351332-B1 | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1993-03-24 | — | — | EP | disclosed |
| US-5123953-A | DIHALOGENATED HERBICIDAL SULPHONES | RHONE-POULENC AGROCHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5100460-A | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1992-03-31 | — | — | US | disclosed |
| EP-0398818-A1 | Dihalogenated herbicidal sulfones | RHONE-POULENC AGROCHIMIE (FR) | 1990-11-22 | — | — | EP | disclosed |
| EP-0351332-A1 | Herbicidal compounds and compositions containing them | RHONE-POULENC AGROCHIMIE (FR) | 1990-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221766-A1 | METHOD FOR PRODUCING FLUORINATED COMPOUND | AFF2, AFF1, AFF4 | HSD11B1 657/4885RECQL 609/4885POLB 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.