Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667643 | 0.85 | CA9 (0.51) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL8667501 | 0.84 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL8047953 | 0.84 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL8670248 | 0.83 | L3MBTL1 (0.44) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL8047912 | 0.81 | L3MBTL1 (0.38) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL8047931 | 0.80 | CA9 (0.51) | HDAC1HDAC2CA12CA9NPC1 | |
| SCHEMBL8671281 | 0.80 | HDAC1 (0.49) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL8047949 | 0.78 | CHRM5 (0.38) | — | |
| SCHEMBL8667683 | 0.76 | HDAC1 (0.38) | ADRA1DADRA1AADRA1BHDAC1HDAC2 | |
| SCHEMBL9659666 | 0.76 | CA12 (0.50) | HDAC1HDAC2CA12CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760054-A | BENIGN PROSTATIC HYPERTROPHY | MERCK & CO., INC. (US) | 1998-06-02 | — | — | US | disclosed |