Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091240 | 1.00 | MAPT (0.40) | MAPTMIFAAK1RAB9ASMN1; SMN2 | |
| SCHEMBL4091245 | 1.00 | MAPT (0.40) | MAPTMIFAAK1RAB9ASMN1; SMN2 | |
| SCHEMBL11374315 | 0.88 | PTGS2 (0.40) | MAPTAAK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9078939 | 0.85 | MIF (0.40) | MAPTMIFRAB9ASMN1; SMN2RECQL | |
| SCHEMBL9077488 | 0.85 | MIF (0.40) | MAPTMIFRAB9ASMN1; SMN2RECQL | |
| SCHEMBL9077491 | 0.85 | MIF (0.40) | MAPTMIFRAB9ASMN1; SMN2RECQL | |
| SCHEMBL12865426 | 0.85 | MIF (0.40) | MAPTMIFRAB9ASMN1; SMN2RECQL | |
| SCHEMBL4092065 | 0.83 | KDM4E (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4092067 | 0.83 | KDM4E (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11119176 | 0.82 | MIF (0.45) | MAPTMIFAAK1RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |
| US-4277395-A | OF ELASTASE; OLIGOPEPTIDES | RICHARDSON-MERRELL INC. (US) | 1981-07-07 | — | — | US | disclosed |