Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12865426 | 1.00 | MIF (0.40) | MIFCYP3A4NFKB1SMN1; SMN2CYP2C9 | |
| SCHEMBL9077491 | 1.00 | MIF (0.40) | MIFCYP3A4NFKB1SMN1; SMN2CYP2C9 | |
| SCHEMBL9077488 | 1.00 | MIF (0.40) | MIFCYP3A4NFKB1SMN1; SMN2CYP2C9 | |
| SCHEMBL8667692 | 0.85 | MAPT (0.40) | MIFNFKB1SMN1; SMN2NPC1RECQL | |
| SCHEMBL4091240 | 0.85 | MAPT (0.40) | MIFNFKB1SMN1; SMN2NPC1RECQL | |
| SCHEMBL4091245 | 0.85 | MAPT (0.40) | MIFNFKB1SMN1; SMN2NPC1RECQL | |
| SCHEMBL6992245 | 0.83 | NOS2 (0.49) | MIFRECQLMAPTLMNAALDH1A1 | |
| SCHEMBL7420415 | 0.83 | NOS2 (0.49) | MIFRECQLMAPTLMNAALDH1A1 | |
| SCHEMBL7420416 | 0.83 | NOS2 (0.49) | MIFRECQLMAPTLMNAALDH1A1 | |
| SCHEMBL6992247 | 0.83 | NOS2 (0.49) | MIFRECQLMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590089-B2 | Processes for preparing toll-like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20240239816-A1 | BORONO-PHENYLALANINE DERIVATIVE | STELLA PHARMA CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| EP-4361159-A1 | BORONO-PHENYLALANINE DERIVATIVE | Stella Pharma Corporation (JP) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022270143-A1 | BORONO-PHENYLALANINE DERIVATIVE | ステラファーマ株式会社 | 2022-12-29 | — | — | WO | disclosed |
| US-20220274985-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2022-09-01 | — | — | US | disclosed |
| EP-3990455-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-05-04 | — | — | EP | disclosed |
| US-11286257-B2 | Processes for preparing toll-like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3461816-B1 | FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20210017170-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-21 | — | — | US | disclosed |
| US-9409866-B2 | Pyridine-2-amides useful as CB2 agonists | HOFFMANN-LA ROCHE INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150376136-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| EP-2958897-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| US-20150344429-A1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-12-03 | — | — | US | disclosed |
| EP-2928867-A1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014130582-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-2014086805-A1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-12 | — | — | WO | disclosed |
| US-8507669-B2 | Optically active dibenzazepine derivatives | NIPPON SODA CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-5554753-A | Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis | INDIANA UNIVERSITY FOUNDATION (US) | 1996-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | DRD1, DRD4, DRD2 | MIF 3961/4885CYP3A4 113/4885NFKB1 1790/4885 |
| US-12590089-B2 | Processes for preparing toll-like receptor modulator compounds | TLR8, MYD88, TLR6 | MIF 20/4885CYP3A4 4572/4885NFKB1 246/4885 |
| US-20150344429-A1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | CNR2, CNR1, GPR52 | MIF 4657/4885CYP3A4 649/4885NFKB1 2359/4885 |
| US-20150376136-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPA1 | MIF 2223/4885CYP3A4 1940/4885NFKB1 3891/4885 |
| US-20240239816-A1 | BORONO-PHENYLALANINE DERIVATIVE | SLC7A1, SLC1A5, LATS2 | MIF 4297/4885CYP3A4 2084/4885NFKB1 1644/4885 |
| US-20220274985-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | TLR4, TLR3, TLR6 | MIF 232/4885CYP3A4 2667/4885NFKB1 179/4885 |
| US-20210017170-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | TLR4, TLR3, TLR6 | MIF 232/4885CYP3A4 2667/4885NFKB1 179/4885 |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | MIF 2223/4885CYP3A4 1940/4885NFKB1 3891/4885 |
| US-11286257-B2 | Processes for preparing toll-like receptor modulator compounds | TLR4, TLR3, TLR6 | MIF 232/4885CYP3A4 2667/4885NFKB1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.