Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092067 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL28883793 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL4091240 | 0.83 | MAPT (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8667692 | 0.83 | MAPT (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4091245 | 0.83 | MAPT (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29033254 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL11374315 | 0.81 | PTGS2 (0.40) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4111358 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL4111352 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL12865426 | 0.78 | MIF (0.40) | KDM4EALDH1A1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221640-A1 | Novel Crystal Modifications | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
| US-20090221640-A1 | Novel Crystal Modifications | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221640-A1 | Novel Crystal Modifications | PTMS, NT5C, CDK5 | KDM4E 161/4885ALDH1A1 1028/4885L3MBTL1 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.