Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.48 |
| ▸ | HEXA | P06865 | 5/20 | 0.46 |
| ▸ | HEXB | P07686 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671343 | 0.88 | KLK7 (0.51) | KLK7FTOHEXAHEXBMEN1 | |
| SCHEMBL8668083 | 0.88 | KLK7 (0.53) | KLK7FTOHEXAHEXBMEN1 | |
| SCHEMBL8668325 | 0.82 | HEXA (0.53) | FTOHEXAHEXBMEN1KMT2A | |
| SCHEMBL8031989 | 0.81 | HEXA (0.69) | HEXAHEXBMEN1KMT2AKDM4E | |
| SCHEMBL14557208 | 0.81 | KLK7 (0.57) | KLK7FTOHEXAHEXBMEN1 | |
| SCHEMBL8670307 | 0.80 | CYP2D6 (0.61) | FTOHEXAHEXBMEN1KMT2A | |
| SCHEMBL11440392 | 0.80 | FTO (0.71) | KLK7FTOHEXAHEXBMEN1 | |
| SCHEMBL8395426 | 0.79 | SIRT1 (0.65) | KLK7FTOHEXAHEXBMAPT | |
| SCHEMBL3851575 | 0.79 | KMT2A (0.67) | KLK7FTOMEN1KMT2AKDM4E | |
| SCHEMBL8671345 | 0.78 | KLK7 (0.52) | KLK7FTOMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789418-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |