Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.59 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | HEXA | P06865 | 6/20 | 0.55 |
| ▸ | HEXB | P07686 | 6/20 | 0.55 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031989 | 0.88 | HEXA (0.69) | MEN1POLBKMT2ANPSR1MAPT | |
| SCHEMBL8668325 | 0.87 | HEXA (0.53) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL2365312 | 0.86 | HEXA (0.74) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL8670304 | 0.85 | CYP2D6 (0.64) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL8670977 | 0.83 | FTO (0.63) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL8671682 | 0.81 | HEXA (0.71) | MEN1POLBKMT2AMAPTRAB9A | |
| SCHEMBL8668087 | 0.80 | KLK7 (0.51) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL9502888 | 0.78 | HEXA (0.73) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL9092319 | 0.77 | SIRT1 (0.63) | CYP2D6FTOMEN1POLBKMT2A | |
| SCHEMBL8670400 | 0.77 | HEXA (0.53) | MEN1POLBKMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789418-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |