Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 4/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668739 | 0.91 | ACE (0.47) | SIGMAR1TLR2TLR1ACEKDM1A | |
| SCHEMBL8671320 | 0.85 | SIGMAR1 (0.41) | SIGMAR1TLR2TLR1ACERAB9A | |
| SCHEMBL8672121 | 0.84 | SIGMAR1 (0.45) | SIGMAR1TLR2TLR1ACETSHR | |
| SCHEMBL8666870 | 0.84 | SIGMAR1 (0.43) | SIGMAR1TLR2TLR1ACEKDM1A | |
| SCHEMBL8668252 | 0.80 | SIGMAR1 (0.39) | SIGMAR1TLR2TLR1ACETSHR | |
| SCHEMBL8670628 | 0.79 | SIGMAR1 (0.41) | SIGMAR1TLR2TLR1ACETSHR | |
| SCHEMBL8668231 | 0.79 | SIGMAR1 (0.41) | SIGMAR1TLR2TLR1ACETSHR | |
| SCHEMBL8671884 | 0.78 | ACE (0.46) | SIGMAR1ACEKDM1AMAOBCYP3A4 | |
| SCHEMBL8870406 | 0.77 | ACE (0.53) | ACE | |
| SCHEMBL8668741 | 0.77 | ACE (0.53) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |