Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668227 | 0.91 | SIGMAR1 (0.42) | ACESIGMAR1TLR2TLR1KDM1A | |
| SCHEMBL8671320 | 0.90 | SIGMAR1 (0.41) | ACESIGMAR1TLR2TLR1KMT2A | |
| SCHEMBL8672121 | 0.89 | SIGMAR1 (0.45) | ACESIGMAR1TLR2TLR1KMT2A | |
| SCHEMBL8666870 | 0.88 | SIGMAR1 (0.43) | ACESIGMAR1TLR2TLR1KDM1A | |
| SCHEMBL8670628 | 0.88 | SIGMAR1 (0.41) | ACESIGMAR1TLR2TLR1KMT2A | |
| SCHEMBL8668231 | 0.83 | SIGMAR1 (0.41) | ACESIGMAR1TLR2TLR1KMT2A | |
| SCHEMBL8870576 | 0.81 | HSD17B10 (0.47) | ACESIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8870503 | 0.81 | HSD17B10 (0.47) | ACESIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8870406 | 0.81 | ACE (0.53) | ACE | |
| SCHEMBL8668741 | 0.81 | ACE (0.53) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |