SCHEMBL8668228

SCHEMBL8668228

CC(=O)CCSc1nc(C)c(C(C)=O)s1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
HSD17B10 Q99714 2/20 0.44
RXFP1 Q9HBX9 2/20 0.43
HPGD P15428 2/20 0.40
CYP1A2 P05177 1/20 0.39
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
APEX1 P27695 1/20 0.39
RAB9A P51151 5/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
NPC1 O15118 3/20 0.38
TSHR P16473 2/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2210099 0.84 ALDH1A1 (0.44) ALDH1A1HSD17B10RXFP1HPGDCYP1A2
SCHEMBL2213342 0.79 ALDH1A1 (0.52) ALDH1A1HSD17B10RXFP1HPGDCYP1A2
SCHEMBL9749534 0.77 APEX1 (0.54) ALDH1A1HSD17B10RXFP1HPGDGAA
SCHEMBL16907286 0.77 RXFP1 (0.46) ALDH1A1HSD17B10RXFP1HPGDCYP1A2
SCHEMBL6113785 0.75 LMNA (0.46) ALDH1A1HSD17B10RXFP1HPGDCYP1A2
SCHEMBL9749375 0.73 ALDH1A1 (0.45) ALDH1A1HSD17B10HPGDCYP1A2GAA
SCHEMBL9749606 0.72 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDGAAAPEX1
SCHEMBL7260097 0.70 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDRAB9ASMN1; SMN2
SCHEMBL13629729 0.68 SMN1; SMN2 (0.76) ALDH1A1HSD17B10HPGDCYP1A2CYP2C9
SCHEMBL9748472 0.67 ALDH1A1 (0.54) ALDH1A1HSD17B10HPGDGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759187-B1 PROCESS FOR MANUFACTURING STABLE PHOTOTHERMOGRAPHIC ELEMENTS IMATION CORP (US) 1998-10-21 EP disclosed
EP-0759187-A1 PROCESS FOR MANUFACTURING STABLE PHOTOTHERMOGRAPHIC ELEMENTS Imation Corp. (US) 1997-02-26 EP disclosed
WO-1995029429-A1 PROCESS FOR MANUFACTURING STABLE PHOTOTHERMOGRAPHIC ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-02 WO disclosed
US-5405740-A Multilayer coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-11 US disclosed