Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7942179 | 0.98 | MAPT (0.46) | MAPTALDH1A1SCN5ASCN2APPIA | |
| SCHEMBL11440641 | 0.84 | JAK2 (0.53) | MAPTALDH1A1SCN5ASCN2APPIA | |
| SCHEMBL5467787 | 0.83 | GAA (0.49) | ALDH1A1PPIAJAK2TYK2HPGD | |
| SCHEMBL8416208 | 0.79 | POLB (0.60) | ALDH1A1PPIAHPGDKMT2AGAA | |
| Hydrochloric Acid SCHEMBL8391036 | 0.79 | P2RX7 (0.51) | ALDH1A1SCN5ASCN2AJAK2KMT2A | |
| Hydrochloric Acid SCHEMBL8390597 | 0.78 | KDM4E (0.63) | MAPTALDH1A1PPIAHPGDKMT2A | |
| SCHEMBL5467789 | 0.76 | KDM4E (0.65) | MAPTALDH1A1SCN5ASCN2APPIA | |
| Hydrochloric Acid SCHEMBL8390632 | 0.76 | KMT2A (0.47) | ALDH1A1PPIAJAK2TYK2HPGD | |
| SCHEMBL4377125 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1JAK2TYK2HPGD | |
| SCHEMBL21884596 | 0.75 | CYP3A4 (0.39) | ALDH1A1SCN5ASCN2ACYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025269-B1 | ANTI-DIARRHOEA VETERINARY COMPOSITION | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | claimed |
| JP-10081662-A | — | — | None | — | — | JP | disclosed |
| JP-H1081662-A | BIS-ORTHO-SUBSTITUTED BENZOYLGUANIDINE, ITS PRODUCTION, ITS USE AS MEDICINE OR DIAGNOSTIC AGENT AND MEDICINE CONTAINING THE COMPOUND | HOECHST AG | 1998-03-31 | — | — | JP | disclosed |