Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 5/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724179 | 1.00 | MAOA (0.56) | MAOAMAOBALOX5AHRABCG2 | |
| SCHEMBL8668546 | 1.00 | MAOA (0.56) | MAOAMAOBALOX5AHRABCG2 | |
| SCHEMBL15613 | 1.00 | — | — | |
| SCHEMBL125113 | 1.00 | MAOA (0.56) | MAOAMAOBALOX5AHRABCG2 | |
| SCHEMBL3102452 | 1.00 | MAOA (0.56) | MAOAMAOBALOX5AHRABCG2 | |
| SCHEMBL8671027 | 1.00 | MAOA (0.56) | MAOAMAOBALOX5AHRABCG2 | |
| SCHEMBL29383458 | 1.00 | MAOA (0.56) | MAOAMAOBALOX5AHRABCG2 | |
| Water SCHEMBL1286428 | 0.96 | MAOA (0.53) | MAOAMAOBALOX5AHRABCG2 | |
| Hydrochloric Acid SCHEMBL7263461 | 0.96 | MAOA (0.53) | MAOAMAOBALOX5AHRABCG2 | |
| Hydrochloric Acid SCHEMBL5958364 | 0.96 | MAOA (0.53) | MAOAMAOBALOX5AHRABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173803-B2 | Supramolecular scaffolds and methods of making the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173803-B2 | Supramolecular scaffolds and methods of making the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | BLM, TBXAS1, TOP2B | MAOA 1246/4885MAOB 723/4885ALOX5 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.