Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177323 | 0.75 | PTPN1 (0.45) | PPARGMCL1 | |
| SCHEMBL8304179 | 0.72 | MCL1 (0.41) | PPARGMCL1 | |
| SCHEMBL8405115 | 0.72 | MTNR1A (0.38) | PPARG | |
| SCHEMBL8405118 | 0.72 | MTNR1A (0.38) | PPARG | |
| SCHEMBL7824812 | 0.71 | ALOX5 (0.34) | PPARGMCL1FFAR1 | |
| SCHEMBL8309388 | 0.71 | PPARG (0.44) | PPARGMCL1FFAR1 | |
| SCHEMBL8306634 | 0.70 | CTRB1 (0.41) | — | |
| SCHEMBL8857154 | 0.69 | PPARG (0.43) | PPARGMCL1FFAR1 | |
| SCHEMBL27516237 | 0.69 | MAPT (0.51) | PPARG | |
| SCHEMBL1130751 | 0.68 | PPARG (0.49) | PPARGMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834501-A | TREATING DIABETES OR HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |