Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555266 | 0.82 | HDAC4 (0.41) | TSHRHDAC4MEF2DMAPTKDM4E | |
| SCHEMBL8671683 | 0.81 | ALDH1A1 (0.52) | HTR6MAOBMAOAHDAC4MEF2D | |
| SCHEMBL12838129 | 0.78 | TSHR (0.39) | TSHRHTR6APPHDAC4MAPT | |
| SCHEMBL12707605 | 0.77 | TSHR (0.54) | TSHRHTR6APPMAPTKDM4E | |
| SCHEMBL8560494 | 0.77 | HDAC4 (0.35) | HDAC4MEF2DSMN1; SMN2ALDH1A1 | |
| SCHEMBL28387332 | 0.77 | ALDH1A1 (0.42) | TSHRAPPMAPTKDM4ECYP3A4 | |
| SCHEMBL25659414 | 0.75 | APP (0.37) | TSHRHTR6APPMAOBHDAC4 | |
| SCHEMBL18905641 | 0.75 | TSHR (0.48) | TSHRHTR6APPMAPTKDM4E | |
| SCHEMBL69726 | 0.74 | MAOB (0.57) | TSHRMAOBMAOACYP3A4TAAR1 | |
| SCHEMBL7047409 | 0.74 | TSHR (0.42) | TSHRHTR6APPHDAC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |