Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555266 | 0.84 | HDAC4 (0.41) | HDAC4MEF2DALDH1A1SMN1; SMN2 | |
| SCHEMBL18976805 | 0.80 | ALDH1A1 (0.39) | HDAC4MEF2DNR3C1S1PR1CNR2 | |
| SCHEMBL8668658 | 0.77 | TSHR (0.43) | HDAC4MEF2DALDH1A1SMN1; SMN2 | |
| SCHEMBL5543744 | 0.73 | ALDH3A1 (0.53) | ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL610689 | 0.70 | TP53 (0.46) | S1PR1ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL11130027 | 0.69 | ALDH1A1 (0.41) | HDAC4MEF2DNR3C1ALDH3A1ALDH1A3 | |
| SCHEMBL12838129 | 0.67 | TSHR (0.39) | HDAC4SMN1; SMN2 | |
| SCHEMBL31657712 | 0.67 | ALDH1A1 (0.55) | HDAC4MEF2DNR3C1ALDH1A1LMNA | |
| SCHEMBL4377348 | 0.67 | ALDH1A1 (0.55) | HDAC4MEF2DNR3C1ALDH1A1LMNA | |
| SCHEMBL9690315 | 0.67 | MAPT (0.44) | HDAC4MEF2DNR3C1S1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815108-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |