Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ARG2 | P78540 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712652 | 0.85 | MAOB (0.48) | MAOBALDH1A1CA1CA2ARG2 | |
| SCHEMBL8199494 | 0.84 | MAOB (0.46) | MAOBALDH1A1CA1CA2ARG2 | |
| SCHEMBL5852576 | 0.84 | MAOB (0.52) | MAOBALDH1A1CYP2A6TSHRLOXL2 | |
| SCHEMBL8196750 | 0.84 | G6PC1 (0.49) | MAOBG6PC1TSHRL3MBTL1HSD17B10 | |
| SCHEMBL3241749 | 0.84 | LMNA (0.42) | MAOBALDH1A1CYP2A6TSHRIDO1 | |
| SCHEMBL8840747 | 0.84 | SIGMAR1 (0.44) | MAOBALDH1A1G6PC1TSHRIDO1 | |
| SCHEMBL654153 | 0.84 | NFE2L2 (0.52) | MAOBALDH1A1TSHRTRPA1L3MBTL1 | |
| SCHEMBL6456118 | 0.84 | G6PC1 (0.49) | MAOBALDH1A1G6PC1CYP3A4CYP2C9 | |
| SCHEMBL4348469 | 0.84 | ESR1 (0.45) | MAOBCA1CA2G6PC1IDO1 | |
| SCHEMBL5966235 | 0.84 | CYP1A2 (0.46) | MAOBALDH1A1G6PC1LOXL2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2036 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103351-A | Coronavirus inhibitors | 共晶制药公司 | 2024-05-28 | — | — | CN | claimed |
| EP-3377504-A1 | CYCLAM BASED COMPOUNDS, THEIR CONJUGATES, CO-ORDINATION COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, METHOD OF PREPARATION AND USE THEREOF | Univerzita Karlova (CZ) | 2018-09-26 | — | — | EP | claimed |
| US-10071984-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-09-11 | — | — | US | claimed |
| CN-106512848-B | A kind of cyclic quaternary ammonium salts Gemini surface active agent and preparation method thereof | 武汉工程大学 | 2018-07-17 | — | — | CN | claimed |
| US-20170313661-A1 | KINASE MODULATORS FOR THE TREATMENT OF CANCER | SYNOVO GMBH (DE) | 2017-11-02 | — | — | US | claimed |
| US-9676770-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-06-13 | — | — | US | claimed |
| CN-106512848-A | Cyclic quaternary ammonium salt gemini surfactant and preparation method thereof | 武汉工程大学 | 2017-03-22 | — | — | CN | claimed |
| US-9416123-B2 | Kinase modulators for the treatment of cancer | SYNOVO GMBH (DE) | 2016-08-16 | — | — | US | claimed |
| CN-105845739-A | Two-dimensional nano sheet layer transition metal sulfide bidirectional switch device | 天津理工大学 | 2016-08-10 | — | — | CN | claimed |
| EP-1294699-B1 | MODULATORS OF TNF- ALPHA SIGNALLING | GENZYME CORP (US) | 2016-04-13 | — | — | EP | claimed |
| EP-0243645-A2 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | claimed |
| EP-0221516-A1 | 7-(Aryloxy)-2-quinolyloxy-alkane-acid derivatives, process for their preparation and herbicides containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-05-13 | — | — | EP | claimed |
| EP-0194464-A1 | Amino acid derivatives and use thereof for the preparation of an anticonvulsant | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1986-09-17 | — | — | EP | claimed |
| EP-0179015-A1 | 7-(Aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-23 | — | — | EP | claimed |
| US-4552969-A | 3-Alkanoyl benzothiazoline compounds useful for treating cardiovascular disease | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | claimed |
| US-4419490-A | GROUP 8 METAL | HEYL & CO. CHEMISCH-PHARMAZEUTISCHE FABRIK (DE) | 1983-12-06 | — | — | US | claimed |
| US-4277480-A | DISORDERS OF CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1981-07-07 | — | — | US | claimed |
| EP-0001644-A1 | N-substituted mercaptoacetamidines and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1979-05-02 | — | — | EP | claimed |
| US-4144271-A | IMMUNOREGULANTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | claimed |
| US-3995059-A | CHOLESTEROL LOWERING AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-30 | — | — | US | claimed |