Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551948 | 0.87 | ADORA2B (0.46) | USP2CYP3A4ADORA2BADORA2APDE4A | |
| SCHEMBL8668367 | 0.80 | MEN1 (0.53) | HTTLMNAUSP2CYP3A4MEN1 | |
| SCHEMBL4413622 | 0.80 | ADORA2B (0.39) | HTTLMNAUSP2CYP3A4ADORA2B | |
| SCHEMBL4552370 | 0.76 | ADORA2B (0.37) | HTTLMNAUSP2CYP3A4ADORA2B | |
| SCHEMBL3115778 | 0.75 | CYP1A2 (0.52) | HTTLMNAUSP2CYP3A4ADORA2B | |
| SCHEMBL4415172 | 0.73 | ADORA2B (0.39) | HTTLMNAUSP2CYP3A4ADORA2B | |
| SCHEMBL874074 | 0.73 | TSHR (0.39) | HTTADORA2BADORA2APDE4APDE4B | |
| SCHEMBL872374 | 0.72 | ADORA2A (0.40) | LMNAADORA2BADORA2APDE4APDE4B | |
| SCHEMBL8673254 | 0.71 | TRAP1 (0.52) | ADORA2ATK1 | |
| 1,4-Butanediol SCHEMBL11143138 | 0.71 | CYP3A4 (0.73) | HTTLMNAUSP2CYP3A4ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786359-A | IMMUNOSTIMULANTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-28 | — | — | US | disclosed |