Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 14/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 10/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629388 | 0.96 | TRAP1 (0.53) | TRAP1HSP90B1HSP90AA1ADORA2A | |
| SCHEMBL872294 | 0.90 | TRAP1 (0.55) | TRAP1HSP90B1HSP90AA1TLR7ADORA2A | |
| SCHEMBL5173890 | 0.84 | TRAP1 (0.53) | TRAP1HSP90B1HSP90AA1TLR7ADORA2A | |
| SCHEMBL23991310 | 0.83 | TLR7 (0.46) | TRAP1HSP90B1HSP90AA1TLR7ADORA2A | |
| SCHEMBL23991311 | 0.81 | ALDH1A1 (0.39) | TRAP1HSP90B1HSP90AA1ADORA2A | |
| SCHEMBL4551932 | 0.74 | TRAP1 (0.54) | TRAP1HSP90B1HSP90AA1ADORA2A | |
| SCHEMBL8668697 | 0.71 | HTT (0.37) | TK1ADORA2A | |
| SCHEMBL23629397 | 0.70 | TRAP1 (0.43) | TRAP1HSP90B1HSP90AA1TLR7ADORA2A | |
| SCHEMBL29723515 | 0.69 | TRAP1 (0.43) | TRAP1HSP90B1HSP90AA1TLR7ADORA2A | |
| SCHEMBL23498154 | 0.69 | TRAP1 (0.43) | TRAP1HSP90B1HSP90AA1TLR7ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786359-A | IMMUNOSTIMULANTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-28 | — | — | US | disclosed |