Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666936 | 0.85 | LMNA (0.44) | POLBALDH1A1MAPTBDKRB2LMNA | |
| SCHEMBL8565508 | 0.84 | BDKRB2 (0.56) | BDKRB2 | |
| SCHEMBL8667851 | 0.84 | MEN1 (0.44) | POLBALDH1A1BDKRB2KMT2AKDM4E | |
| SCHEMBL8666921 | 0.82 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL8367312 | 0.82 | BDKRB2 (0.52) | POLBBDKRB2 | |
| SCHEMBL8666299 | 0.81 | BDKRB2 (0.42) | POLBMAPTBDKRB2KMT2AKDM4E | |
| SCHEMBL8666404 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1MAPTBDKRB2KMT2AKDM4E | |
| SCHEMBL8563482 | 0.78 | PPARG (0.42) | — | |
| SCHEMBL8666464 | 0.78 | BDKRB2 (0.40) | ALDH1A1BDKRB2KDM4ESMN1; SMN2 | |
| SCHEMBL8666461 | 0.77 | PPARG (0.46) | ALDH1A1MAPTBDKRB2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |