Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943164 | 0.81 | PKM (0.42) | MEN1KMT2APKMATMHSD17B10 | |
| SCHEMBL6446128 | 0.76 | KMT2A (0.46) | USP2TP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL4048240 | 0.69 | KMT2A (0.46) | MEN1KMT2A | |
| SCHEMBL6323522 | 0.66 | CYP2C9 (0.72) | ALDH1A1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL3742035 | 0.66 | MEN1 (0.47) | MEN1KMT2APKMATMHSD17B10 | |
| SCHEMBL18839851 | 0.61 | PKM (0.47) | ALDH1A1MEN1KMT2APKMATM | |
| SCHEMBL1891366 | 0.59 | L3MBTL1 (0.33) | ALDH1A1 | |
| SCHEMBL29993479 | 0.59 | MAPK1 (0.47) | ALDH1A1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL3453024 | 0.58 | POLB (0.39) | ALDH1A1TP53CYP1A2PKMATM | |
| SCHEMBL31621106 | 0.55 | CYP1A2 (0.39) | CYP1A2PKMATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747499-A | CYCLOPENTAQUINAZOLINE COMPOUNDS CYCLOPENTAQUINAZOLINE COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |